Efficacy and safety of statin use in children and adolescents with familial hypercholesterolaemia: a systematic review and meta-analysis of randomized-controlled trials.
Τίτλος | Efficacy and safety of statin use in children and adolescents with familial hypercholesterolaemia: a systematic review and meta-analysis of randomized-controlled trials. |
Publication Type | Journal Article |
Year of Publication | 2020 |
Authors | Anagnostis, P., Vaitsi K., Kleitsioti P., Mantsiou C., Pavlogiannis K., Athyros V. G., Mikhailidis D. P., & Goulis D. G. |
Journal | Endocrine |
Date Published | 2020 Apr 24 |
ISSN | 1559-0100 |
Abstract | PURPOSE: Statins are the mainstay of treatment for patients with familial hypercholesterolaemia (FH). However, their efficacy and safety in children and adolescents with FH has not been well-documented. The purpose of this study was to systematically investigate and meta-analyze the best available evidence from randomized-controlled trials (RCTs) regarding the efficacy and safety of statins in this population. |
DOI | 10.1007/s12020-020-02302-8 |
Alternate Journal | Endocrine |
PubMed ID | 32333266 |