Δημοσίευση

Hemodiafiltration does not have additional benefits over hemodialysis on arterial stiffness, wave reflections and central aortic pressures.

ΤίτλοςHemodiafiltration does not have additional benefits over hemodialysis on arterial stiffness, wave reflections and central aortic pressures.
Publication TypeJournal Article
Year of Publication2014
AuthorsGeorgianos, P. I., Sarafidis P. A., Karpetas A., Kosmidis D., Sioulis A., Liakopoulos V., Stamatiadis D. N., Papagianni A., Zebekakis P. E., Nikolaidis P., & Lasaridis A. N.
JournalBlood Purif
Volume37
Issue1
Pagination18-26
Date Published2014
ISSN1421-9735
Λέξεις κλειδιάAorta, Arterial Pressure, Arteries, Blood Flow Velocity, Female, Hemodiafiltration, Humans, Male, Pulsatile Flow, Renal Dialysis, Vascular Resistance, Vascular Stiffness
Abstract

BACKGROUND/AIMS: The hypothesis that dialytic modality affects arterial stiffness was never investigated. This study includes comparative evaluation of hemodiafiltration versus hemodialysis on arterial function during first and second weekly dialysis sessions.METHODS: 24 patients receiving hemodiafiltration and another 24 age- and sex-matched controls receiving hemodialysis were included. Patients were evaluated before and after first and second weekly dialysis sessions. Applanation tonometry of peripheral arteries was applied to determine aortic and brachial pulse wave velocity and heart rate-adjusted augmentation index (AIx(75)).RESULTS: Hemodiafiltration and hemodialysis reduced AIx(75), but not aortic and brachial pulse wave velocity. Intradialytic reductions in AIx(75) did not differ between hemodiafiltration and hemodialysis in first and mid-week dialysis. In multivariate linear regression, predictors of intradialytic reduction in AIx(75) were changes in body weight and central aortic systolic blood pressure, but not dialytic modality.CONCLUSION: This study showed that hemodiafiltration has similar effects with hemodialysis on wave reflections and stiffness.

DOI10.1159/000355945
Alternate JournalBlood Purif.
PubMed ID24481249

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