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The impact on ovarian reserve after laparoscopic ovarian cystectomy versus three-stage management in patients with endometriomas: a prospective randomized study.

ΤίτλοςThe impact on ovarian reserve after laparoscopic ovarian cystectomy versus three-stage management in patients with endometriomas: a prospective randomized study.
Publication TypeJournal Article
Year of Publication2010
AuthorsTsolakidis, D., Pados G., Vavilis D., Athanatos D., Tsalikis T., Giannakou A., & Tarlatzis B. C.
JournalFertil Steril
Volume94
Issue1
Pagination71-7
Date Published2010 Jun
ISSN1556-5653
Λέξεις κλειδιάAdult, Disease Management, Endometriosis, Female, Humans, Laparoscopy, Oocytes, Ovary, Pilot Projects, Prospective Studies, Treatment Outcome, Young Adult
Abstract

OBJECTIVE: To investigate the effect of two different laparoscopic methods on ovarian reserve in patients with ovarian endometriomas.DESIGN: Prospective, randomized clinical trial.SETTING: Endoscopy unit of a university hospital.PATIENT(S): Twenty women with endometriomas.INTERVENTION(S): Patients were randomly selected to undergo either laparoscopic cystectomy for endometrioma (group 1) or the "three-step procedure" (group 2). Before and 6 months after laparoscopy all patients were evaluated, and 12 months postoperatively they underwent ultrasound scan examination.MAIN OUTCOME MEASURE(S): The primary end point was ovarian reserve damage based on the alterations of anti-Müllerian hormone (AMH). Secondary end points were the changes of antral follicle count and serum concentration of FSH, LH, E(2), and inhibin B.RESULT(S): Mean serum AMH was reduced significantly from 3.9-2.9 ng/mL in group 1 compared with the reduction from 4.5-3.99 ng/mL in group 2.CONCLUSION(S): Ovarian reserve determined by AMH is less diminished after the three-step procedure compared with cystectomy of endometriomas.

DOI10.1016/j.fertnstert.2009.01.138
Alternate JournalFertil. Steril.
PubMed ID19393996

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