Rising Glucagon-Like Peptide 1 Concentrations After Parathyroidectomy in Patients With Primary Hyperparathyroidism.
Τίτλος | Rising Glucagon-Like Peptide 1 Concentrations After Parathyroidectomy in Patients With Primary Hyperparathyroidism. |
Publication Type | Journal Article |
Year of Publication | 2019 |
Authors | Antonopoulou, V., Karras S. N., Koufakis T., Yavropoulou M., Katsiki N., Gerou S., Papavramidis T., & Kotsa K. |
Journal | J Surg Res |
Volume | 245 |
Pagination | 22-30 |
Date Published | 2019 Aug 07 |
ISSN | 1095-8673 |
Abstract | BACKGROUND: Although primary hyperparathyroidism has been associated with insulin resistance, potential optimal effects of parathyroidectomy (PTX) on glucose homeostasis remain controversial. Accordingly, the impact of PTX on glucose-stimulated incretin (glucagon-like peptide 1 [GLP-1] and gastric inhibitory peptide) secretion has not been evaluated. The aim of this pilot study was to compare glucose-stimulated incretin secretion (GSIS) in patients with asymptomatic primary hyperparathyroidism with normal glucose homeostasis, before and after PTX. |
DOI | 10.1016/j.jss.2019.07.019 |
Alternate Journal | J. Surg. Res. |
PubMed ID | 31400574 |