Δημοσίευση

Understanding cardiovascular risk in hemophilia: A step towards prevention and management.

ΤίτλοςUnderstanding cardiovascular risk in hemophilia: A step towards prevention and management.
Publication TypeJournal Article
Year of Publication2016
AuthorsSousos, N., Gavriilaki E., Vakalopoulou S., & Garipidou V.
JournalThromb Res
Volume140
Pagination14-21
Date Published2016 Apr
ISSN1879-2472
Λέξεις κλειδιάAging, Animals, Cardiovascular Diseases, Disease Management, Hemophilia A, Humans, Prevalence, Risk Factors, Thrombosis
Abstract

Advances in hemophilia care have led to increased life expectancy and new challenges in the management of the aging hemophilia population, including cardiovascular risk. Despite the deep knowledge into cardiovascular disease in terms of pathophysiology, risk prediction, prevention, early detection and management gained over the last decades, studies in hemophiliacs are scarce and mainly descriptive. As a growing amount of evidence points towards a similar or increased prevalence of traditional cardiovascular risk factors in hemophilia compared to the general population, the role of non-traditional, disease-related and treatment-related cardiovascular risk factors remains under investigation. Better understanding of cardiovascular risk in hemophilia is mandatory for proper cardiovascular risk prevention and management. Therefore, this review aims to summarize current knowledge on cardiovascular risk in hemophilia patients focusing on a) cardiovascular risk factors (traditional, non-traditional, disease-related and treatment-related), b) cardiovascular morbidity and mortality and c) cardiovascular prevention and management.

DOI10.1016/j.thromres.2016.02.001
Alternate JournalThromb. Res.
PubMed ID27046799

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