International Society on CCHF was created (see at the end of the page)
10-12 September 2017
Makedonia Palace hotel, Thessaloniki, Greece
Under the auspices of the Medical School, Aristotle University of Thessaloniki
Dear colleagues,
On behalf of the Organizing Committee, I’m pleased to invite you to the 2nd International Conference on Crimean-Congo Hemorrhagic Fever, which will be held at the Makedonia Palace Hotel in Thessaloniki, Greece from 10-12 September, 2017.
The conference will give scientists from around the world the chance to exchange information on all aspects of the virus and the disease and report new findings. There will also be the opportunity to compare CCHF with other viral hemorrhagic fevers and discuss common approaches for treatment and prevention.
The city of Thessaloniki has a rich culture, with more than 3000 years of history and many attractive places to visit during your free time.
I encourage you to join us and contribute your knowledge and experience during the 2nd International Conference on CCHF.
Anna Papa, MD PhD
Aristotle University, Thessaloniki
Organizers
Anna Papa, Aristotle University of Thessaloniki, GR
Dimitris Chatzidimitriou, Aristotle University of Thessaloniki, GR
Pantelis Zebekakis , Aristotle University of Thessaloniki, GR
Simeon Metallidis , Aristotle University of Thessaloniki, GR
Scientific Committee
Anna Papa, Aristotle University of Thessaloniki, GR
Ali Mirazimi, Karolinska Institute, National Veterinary Institute and Public Health Agency of Sweden, SE
Mike Bray, Editor-in-chief, Antiviral Research, USA
Heinz Feldmann, National Institutes of Health/National Institute of Allergy and Infectious Diseases, Hamilton, Montana, USA
Felicity Burt, National Health Laboratory Service and University of the Free State, Bloemfontein, SA
Gulay Korukluoglu, Public Health Institutions of Turkey, Ankara, TR
Friedemann Weber, Institute for Virology, Gießen, DE
REGISTRATION
Registration is now open.
Click here to access the registration form
Registration fees*
1. Professional Registration 200.00 EUR
2. Post-Doc registration 150.00 EUR
3. Student Registration 100.00 EUR
Registration includes conference material, coffee breaks, buffet reception (on 10 Sept. 2017) and lunch (on 11 September 2017).
*After June 30, 2017, a late fee of 50 Euros will be added to the registration fees.
Pre-conference trip: Sunday, September 10, 2017 (optional)
Trip to Vergina (75 km west from Thessaloniki) and visit the Archaeological Museum (Royal Tombs). Time: 07.30-12.30. Bus transfer costs 25 Euros; payment as above (by bank transfer or credit card). Admission tickets (12 Euros; for persons >60 years: 6 Euros) will be purchaced at the entrance of the Museum.
Meeting point at the reception of Makedonia Palace Hotel. Departure time: 07.30. Please, try to be on time!
Gala Dinner (optional):
A Gala Dinner with buffet and music is planned at 20.30 on Monday September 11, 2017. It costs 40 Euros per person.
All Payments [registration fee (according to the table), trip to Vergina (25 Euros), dinner (40 Euros)] can be made by:
Bank Transfer
All registration fees should be paid in advance in EUR and made out to ELKE AUTH, mentioning 2nd Int. Conf. CCHF. Please do not forget to indicate your first and last name on the payment.
Account Holder: Eidikos Logariasmos Kondilion Erevnas A.P.TH
IBAN: GR 98 0172 2020 0052 0200 2079 933
Account Number: 5202-002079-933
SWIFT-CODE: PIRBGRAA
Reference: 2nd Int. Conf. CCHF
OR credit card
https://www.rc.auth.gr/
Please do not forget to indicate your first and last name on the payment, and the Reference: 2nd Int. Conf. CCHF
Letter of Confirmation / Payment Receipt
A letter of confirmation will be sent by e-mail once the Congress Secretariat has received the fully completed Registration Form and the related payment(s).
Please, bring this confirmation to the Congress venue in order to receive your Congress name badge and the payment receipt.
Abstract submission
For Abstract submission, please, use Arial font size 10. The title has to be in capital letters and the abstract no longer than 250 words. The full first name, surname and affiliation of all authors should be mentioned.
Please, submit your abstracts through e-mail to ccconf@med.auth.gr indicating whether you prefer oral or poster presentation and the topic which fits best (epidemiology, pathogenesis, clinical, diagnostics, prevention, treatment).
The deadline for the abstract submission is 10 June 2017. Abstract submission ended.
Program at a glance
Sunday, September 10, 2017 |
|
12.00-13.00 |
Registration and set up of Posters |
13.00-13.30 |
Welcome |
13.30-16.20 |
EPIDEMIOLOGY IN HUMANS |
16.20-16.45 |
Coffee break and poster viewing |
16.45-18.15 |
TICKS AND VIRUS-TICK INTERACTIONS |
18.30-19.00 |
Social lecture: Aristotle’s view on Life |
19.15 |
Reception (buffet at Makedonia Palace hotel) |
Monday, September 11, 2017 |
|
08.15-09.00 |
WILD AND DOMESTIC ANIMAL HOSTS |
09.00-10.00 10.00-10.30 |
CCHF Society Coffee break and poster viewing |
10.30-11.45 11.45-12.45 |
MOLECULAR VIROLOGY Discussion on CCHFV Taxonomy |
12.45-14.00 |
Lunch and poster viewing |
14.00-16.15 |
PATHOGENESIS AND ANIMAL MODELS |
16.15-16.45 |
Coffee break and poster viewing |
16.45-18.30 |
CLINICAL ASPECTS-DIAGNOSTICS |
20.00 |
Gala dinner with music (optional) |
Tuesday, September 12, 2017 |
|
08.30-10.15 |
CLINICAL MANAGEMENT- CLINICAL TRIALS |
10.15-10.45 |
Coffee break and poster viewing |
10.45-12.00 |
PREVENTION IN HUMANS |
12.00-13.30 |
WHAT'S NEXT? |
13.30 |
Conclusions and Farewell |
Accommodation options
1. Makedonia Palace hotel (place of the Conference) hold a reserved contingent of limited rooms at special rates. Please, visit:
https://makedoniapalace.reserve-online.net/?bkcode=AUTHESS&checkin=2017-09-09
and quote the special conference booking code "AUTHESS" when booking so that you may benefit from the special conference rates.
2. ABC Hotel (http://www.hotelabc.gr/)
For 8 and 9 September 2017
75€ for single room, 88 € for double room
For 10 and 11 September 2017
68€ for single room, 80 € for double room
All prices include buffet breakfast.
Please, send e-mail (info@hotelabc.gr) or fax (+30-2310-276542) and quote the special conference booking code "AUTHESS" when booking so that you may benefit from the special conference rates.
There are several hotels in Thessaloniki. We recommend you to book early your accommodation since the International Fair is taking place at the same time.
Please, note that attendees are responsible for their own hotel reservations and costs.
FINAL PROGRAM
Sunday September 10, 2017
12.00-13.00 Registration and set-up of posters
13.00-13.30 Welcome to Thessaloniki
Anna Papa
Welcome address from Aristotle University of Thessaloniki
Prof. Pericles Mitkas, Rector of Aristotle University of Thessaloniki
Prof. Giorgos Karakioulakis, Dean of the Faculty of Health Sciences
Prof. Alexandros Garyfallos, Head of the Medical School
EPIDEMIOLOGY OF CCHF IN HUMANS
Chairpersons: Anna Papa, Gülay Korukluoğlu
13.30-13.50 CCHF in Turkey
Gülay Korukluoğlu
13.50-14.10 Epidemiology of CCHF in India
Pragya Yadav
14.10-14.30 Changing epidemiology of CCHF in Pakistan
Bushra Jamil Ali
14.30-14.45 CCHF in Bulgaria
Iva Christova
14.45-15.00 CCHFV in Spain
Maria Paz Sanchez-Seco Farinas, A.I. Negrado Anton, E.R. de Arellano,
F. Lasala, A. Estrada, M.A. Habela
15.00-15.15 CCHF in Mongolia
M.A. Voorhees, S.L. Padilla, D. Jamsransuren, J.W. Koehler, K. Delp,
D. Adiyadorj, U. Baasandagwa, B. Jigjav, T.D. Minogue, Randal J. Schoepp
15.15-15.30 CCHF in Georgia
N. Mamuchishvili, K. Zakhashvili, Giorgi Chakhunashvili, P. Imnadze,
M. Keshtkar-Jahromi, D. Pecor, R. Rivard
15.30-15.45 Epidemiological study of CCHF in Tunesia
F. Wasfi, S. Dowall, C. Najar, T.l Ben Slimane, T. Ghabbari, A. Bosworth,
M. Chakroun, A. Varghese, H. Tiouiri, M. Ben Jemaa, A. Znazen,
R. Hewson, A. Letaief, M. Petretto, Elyas Zhioua
15.45-15.55 Risk-based model for the forcast of the epidemiological situation
of CCHF in the Russian Federation (a study of the Stavropol region)
Vlandimir Dubyanskiy, O. Maletskaya, D. Prislegina, A. Kulichenko
15.55-16.05 Molecular epidemiology of CCHF in Russia
A. Volynkina, E. Kotenev, Y. Lisitskaya, Olga Maletskaya, A. Kulichenko
16.05-16.20 CCHF in Western Asia: current situation demonstrates a need
for more robust surveillance
Maryam Keshtkar-Jahromi, A. Buffum, M.G. Kortepeter, D. Pecor,
D.A. Apanaskevich, S. Mate, Jens H. Kuhn, G. Palacios
16.20-16.45 Coffee break and poster viewing
TICKS AND VIRUS-TICK INTERACTIONS
Chairpersons: Agustín Estrada-Peña, Dennis Bente
16.45-17.15 The role of ticks in the maintenance and transmission of CCHFV
Agustín Estrada-Peña, ES
17.15-17.45 CCHFV tick research in maximum biocontainment: challenges
and current findings
Dennis Bente, USA
17.45-18.00 Detection of AP92-related CCHFV strains in field-collected ticks
from Meditterramean and Eastern Anatolia
E. Dinçer, O. Hekimoğlu, Sabri Hacıoğlu, K. Földes, Z. Karapınar, P.F. Polat,
B. Oğuz, Ö.O. Kılınç, A. Özkul, K. Ergünay
18.00-18.15 Isolation and next generation sequencing of an AP92-like CCHFV
strain in Greece
Αnna Papa, E. Papadopoulou, Κ. Tsioka, Α. Kontana, A. Melidou, Ε. Gavana,
Ν. Giadinis
SOCIAL lecture
Chairpersons: Pantelis Zembekakis, Simeon Metallidis
18.30-19.00 Aristotle’s view oF Life
Zacharias Skouras, GR
19.15 Reception (buffet at Makedonia Palace hotel)
Monday September 11, 2017
WILD AND DOMESTIC ANIMAL HOSTS
Chairpersons: Martin Groschup, Aykut Ozkul
08.15-08.45 Assaying animals to reveal CCHFV infection risks
Martin Groschup, DE
08.45-09.00 Role of wild birds and domestic ruminants in local
CCHFV epidemiology in Turkey
Sabri Hacioglu, E. Ozan, K. Ergunay, A. Ozkul
ESTABLISHMENT OF AN INTERNATIONAL SOCIETY ON CCHF
09.00-10.00 Aims and scope, By-laws, Elections
10.00-10.30 Coffee break and poster viewing
MOLECULAR VIROLOGY
Chairpersons: Friedemann Weber, Stuart Nichol
10.30-11.00 A reverse genetics toolkit to gain insights into CCHFV pathogenicity
and for the generation of vaccine candidates
Eric Bergeron, USA
11.00-11.15 Complex interplay between CCHFV ovarian tumor (OTU)
domain and innate immunre response
Stéphanie Devignot, Friedemann Weber
11.15-11.30 The CCHFV-encoded deubiquitinase suppresses the innate
immune response during viral infection
Florine E.M. Scholte, J.V. Dzimianski, J.R. Spengler, S.R. Welch, M. Zivcec,
M. Deaton, S.D. Pegan, S.T. Nichol, C.F. Spiropoulou, Éric Bergeron
11.30-11.45 Preference of CCHFV and Other Nairovirus vOTUs for Interferon-
Stimulated Gene Product 15 Originating from Certain Species
J.V. Dzimianski, M.K. Deaton, O. Goodwin, F. Scholte, E. Bergeron,
Scott D. Pegan
Panel Discussion on CCHFV taxonomic classification
Chairperson: Gustavo Palacios
11.45-12.00 Introduction
Gustavo Palacios, CCHFV Community Working Group, USA
12.00-12.45 Presentations from expert groups - Discussion
12.45-14.00 Lunch
PATHOGENESIS AND ANIMAL MODELS
Chairpersons: Ali Mirazimi, Jessica Spengler
14.00-14.30 Current knowledge of pathogenesis of CCHF
Ali Mirazimi, SE
14.30-15.00 Efforts to develop laboratory animal models of CCHF:
history and current status
Jessica Spengler, USA
15.00-15.30 CCHF Animal modeling (mouse & nonhuman primate)
Elaine Haddock, Heinz Feldmann, USA
15.30-15.45 An in vitro assay to study the molecular pathogenesis
of CCHF
Vanessa Monteil, C. Salata, C. Andersson, A. Mirazimi
15.45-16.00 Evaluation of the biological effects of mutation of the CCHFV
nucleocapsid DEVD domain on viral replication
Cristiano Salata, V. Monteil, H. Karlberg, L. Bell-Sakyi, É. Bergeron,
A. Mirazimi
16.00-16.15 Antibody blockade Of type I interferon signaling for the study
of CCHF in mice
Joseph W. Golden, Michael E. Lindquist, Xiankun Zeng, Charles Shoemaker,
Sharon P. Daye, Jeff Koehler, Aura Garrison
16.15-16.45 Coffee break and poster viewing
CLINICAL ASPECTS AND DIAGNOSTICS
Chairpersons: Bushra Jamil Ali, Felicity Burt
16.45-17.15 Clinical Course of CCHF
Meltem Arzu Yetkin, TR
17.15-17.30 CCHF in Bahawalpur: outbreak investigation and response
Kashif Aziz, PK
17.30-17.45 CCHF in Kosovo from 1989-2016
Salih Ahmeti, I. Dedushaj, P. Emmerich, B. Halili, X. Jakupi, K. Sherifi,
L. Ajazaj-Berisha
17.45-18.00 Novel CCHF molecular diagnostics
L.C. Bonney, Robert J. Watson, B. Afrough, M. Mullojonova, F. Tishkova,
R. Hewson
18.00-18.30 Challenge in development, verification and validation of an IVD-CE
marked assay for the detection of a neglected disease
Markus Heß, altona Diagnostics GmbH
20.30 Gala dinner with music (fee 40 Euros)
Tuesday, September 12, 2017
CLINICAL MANAGEMENT- CLINICAL TRIALS
Chairpersons: Nikki Shindo, Tom Fletcher
08.30-08.50 Clinical aspects of CCHF – Current knowledge and practice
Tom Fletcher, UK
08.50-09.00 Overview of WHO guidelines development for the clinical
management of CCHF
Nikki Shindo, WHO
09.00-09.20 CCHF: an unexpected event in Spain
Marta Mora-Rillo (ES)
09.20-09.40 Efficacy of favipiravir in the treatment of severe fever
with thrombocytopenia syndrome (SFTS) in animal model
and the clinical study on the favipiravir treatment for patients
with SFTS
Masayuki Saijo, T. Azuma, H. Tani, A. Yamanaka, D. Himeji, M. Kawamura,
K. Suemori, T. Haku, H. Ohge, T. Taniguchi, O. Imataki, N. Kadowaki,
M. Shimojima, T. Yoshikawa, T. Kurosu, S. Fukushi, S. Kohno, Y. Furuta,
M. Yasukawa
09.40-09.50 Development of a reporter CCHFV for high-throughput screening
of antiviral compounds
Stephen R. Welch, F.E.M. Scholte, M. Flint, P. Chatterjee, S.T. Nichol,
E. Bergeron, C.F. Spiropoulou
09.50-10.00 Identification of cross-neutralizing monoclonal antibodies against
CCHFV
Marko Zivcec, L.W. Guerrero, C.G. Albariño, É. Bergeron, S.T. Nichol,
C.F. Spiropoulou
10.00-10.15 Discussion
10.15-10.45 Coffee break and poster viewing
PREVENTION IN HUMANS
Chairpersons: Connie Schmaljohn, Roger Hewson
10.45-11.15 CCHFV: a growing threat
Roger Hewson, UK
11.15-11.30 Antibody responses are required for protective adenovirus
vaccination from CCHFV challenge in a lethal disease model
Marko Zivcec, D. Safronetz, D.P. Scott, S. Robertson, H. Feldmann
11.30-11.45 An M-segment-targeting DNA-based vaccine protects against CCHF
in two lethal mouse models
Aura R. Garrison, C.J. Shoemaker, C.J. Fitzpatrick, J.J. Suschak, M.J. Richards,
C.V. Badger, C.M. Six, J.D. Martin, D. Hannaman, M. Zivcec, E. Bergeron,
J.W. Koehler, J. W. Golden, C.S. Schmaljohn
11.45-12.00 In vitro expression of CCHFV surface glycoprotein GC via a plasmid
vector generated as DNA based vaccine
Ergin Sahin, A. Coleri, A. Ozkul
WHAT'S NEXT?
Chairpersons: Pierre Formenty, Mike Bray
12.00-12.30 CCHF R&D blueprint Roadmap Vision
Pierre Formenty, WHO
12.30-13.30 Open Discussion of future research, priorities, immediate needs
13.30 Conclusions and Farewell
POSTERS
1. Evaluation of timelines of outbreak detection and response of CCHF and HFRS in Albania and Southeast European Region
Sylvia Bino, Eugena Tomini, Majlinda Kota, Enkelejda Dikolli, Jonilda Sulo, Kujtim Mersini, Najada Como
2. Detection of two CCHFV genetic lineages in ticks, Albania
A. Papa, E. Velo, P. Kadiaj, Katerina Tsioka, A. Kontana, M. Kota, S. Bino
3. Evaluation of the CCHF results analyzed in Public Health Laboratories IN TURKEY between 2014 and 2017
Yasemin Cosgun, D. Menemenlioglu, D. Yagci Caglayik, F. Bayrakdar, B.G. Giray, S. Havuz, E. Ozmen, A.K. Sıg, G. Korukluoglu
4. Serological testing for CCHFV in putative “Risk groups” - Austria
Hartwig P.Huemer, A. Deutz, A. Posautz, A. Obwaller, T. Perkmann, W. Pöppl, F. Allerberger
5. First serological evidence of CCHFV in humans in Hungary
Nora Magyar, B. Palyi, A. Nagy, I. Damjanova, M. Takacs, Z. Kis
6. CCHF in Iran and Future Challenges
Hossein Bannazadeh Baghi, M. Aghazadeh, M.A. Oskouee
7. More than one-decade phylogenetic analysis of CCHFV in Iran
Sadegh Chinicar, N. Shahhosseini
8. CCHF in Iran: an eighteen years review
M. Mardani, Najmeh Namazee
9. Immunological characteristics of non-structural proteins of CCHFV
E. Karaaslan, Mehmet Z. Doumaz
10. Pathogenesis of CCHFV Kosova Hoti in the Cynomoglus macaque model
Elaine Haddock, G. Saturday, H.Feldmann
11. Protein disulphide isomerase re-localization in CCHF infected cells
Olivier Reynard, Laura Cole, Viktor Volchkov
12. Development of a multiplexed immunoassay to detect IgG antibody responses against CCHFV and hantaviruses within Georgia
Catherine Badger, M. Voorhees, N. Mitaishvili, G. Babuadze, G.Chanturia, R. Schoepp, C. Schmaljohn
13. A one-step multiplex real-time RT-PCR for the universal detection of all CCHFV genotypes
Miriam A. Sas, A. Vina-Rodriguez, M. Mertens, S. Abah, M. Eiden, A. Souley, M.H. Groschup
14. Evaluation of CCHFV nucleoprotein as diagnostic tool in ELISA
M. Yazici, N.S. Cetin, Elif Karaaslan, S. Hasanoglu, M.Z. Doymaz, Ali O. Kilic
15. Delineation of CCHFV pathogenicity by the development of a refined serological assay and the use of reverse genetics
Brian L. Hua, V. Biewener, M. Marklewitz, S. Junglen, S.T. Nichol, C.F. Spiropoulou, E. Bergeron
16. Phylogenetic analysis if whole genome CCHFV strains belonging to lineages Europe 1 and Europe 2
A. Papa, G. Korukluoglu, S. Bino, I. Christova, E. Velo, S. Pappa, A. Melidou
17. Serum level of interferon gamma as a prognostic factor in CCHF
M. Metanat, N. Arbabi, A. Alenabi, E. Pahlavani, M. Rakhshani, Nahidsepehri-Rad, S. Metanat, Batool Sharifi-Mood, M. Keshtkar-Jahromi
18. CCHF in pregnancy - the first reported case in Kosova
Salih Ahmeti, L. Ajazaj-Berisha, B. Halili, V. Berisha, A. Shala
19. The Host Response to CCHFV Infection in Cynomolgus Macaques
David Hawman, E. Haddock, J. Prescott, A. Carmody, H. Feldmann
20. Experimental vaccines for CCHF using pseudotyped and replication-deficient recombinant vesicular stomatitis viruses
Sergio E. Rodriguez, R.W. Cross, C.E. Mire, D.A. Bente, T.W. Geisbert
Board of the International Sociey on CCHF
EXECUTIVE BOARD
President
Anna Papa, Greece
Vice President
Ali Mirazimi, Sweden
Secretary
Roger Hewson, UK
ADVISORY COUNCIL
Heinz Feldmann, USA
Christina Spiropoulou, USA
Dennis Bente, USA
Felicity Burt, South Africa
Dexin Li, China
Silvia Bino, Albania
Iva Christova, Bulgaria
Friedemann Weber, Germany
Salih Ahmeti, Kosovo
Olga Maletskaja, Russia
Gulay Korukluoglu, Turkey
Pragya Yadav, India
Mostafa Salehi Vaziri, Iran
Bushra Jamil, Pakistan