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Combined cardiac surgery and liver transplantation: three decades of worldwide results.

ΤίτλοςCombined cardiac surgery and liver transplantation: three decades of worldwide results.
Publication TypeJournal Article
Year of Publication2011
AuthorsGiakoustidis, A., Cherian T. P., Antoniadis N., & Giakoustidis D.
JournalJ Gastrointestin Liver Dis
Volume20
Issue4
Pagination415-21
Date Published2011 Dec
ISSN1842-1121
Λέξεις κλειδιάAdolescent, Adult, Aged, Aortic Valve Stenosis, Cardiac Surgical Procedures, Cardiomyopathies, Child, Child, Preschool, Coronary Artery Bypass, Coronary Artery Disease, End Stage Liver Disease, Female, Heart Transplantation, Heart Valve Prosthesis Implantation, Humans, Liver Transplantation, Male, Middle Aged, Patient Selection, Risk Assessment, Risk Factors, Treatment Outcome, Young Adult
Abstract

BACKGROUND: Patients with end-stage-liver-disease (ESLD) require orthotopic liver transplantation (OLT) as treatment. However, cirrhotic cardiomyopathy can be clinically revealed during OLT, with the possible development of a transient overt congestive heart failure. A number of patients require a combined procedure of liver transplantation and heart surgery, which includes heart transplantation, aortic valve replacement or coronary artery bypass grafting. Indications for combined liver-heart transplantation include heart failure with associated cardiac cirrhosis, familial amyloidosis, familial hypercholesterolemia and hemochromatosis, and homozygous β-thalassemia. METHODS/RESULTS. We performed a thorough research of Pubmed/ Medline, gathering and discussing data concerning this clinical condition and its treatment.CONCLUSION: In patients with end-stage liver disease, who are unable to tolerate an OLT post-operatively due to cardiac dysfunction, combined cardiac surgery and OLT appears to have certain advantages.

Alternate JournalJ Gastrointestin Liver Dis
PubMed ID22187708

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