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Current and emerging mechanical minimally invasive therapies for benign prostatic obstruction.

ΤίτλοςCurrent and emerging mechanical minimally invasive therapies for benign prostatic obstruction.
Publication TypeJournal Article
Year of Publication2019
AuthorsSountoulides, P., Karatzas A., & Gravas S.
JournalTher Adv Urol
Volume11
Pagination1756287219828971
Date Published2019 Jan-Dec
ISSN1756-2872
Abstract

Transurethral resection of the prostate (TURP) is considered the 'gold standard' for the surgical management of lower urinary tract symptoms (LUTS) due to benign prostatic obstruction (BPO). However, during recent years TURP has been challenged by several minimally invasive therapies (MITs). The reasons for the development of these MITs are the need for anesthesia and the rather unchanged morbidity of TURP, including ejaculation disorders. Mechanical MITs may represent an attractive option for treating LUTS/BPO by using mechanical forces to maintain urethral patency without cutting, ablating, heating or removing prostatic tissue. The present paper provides an update on currently available mechanical devices for the treatment of LUTS/BPO including the prostatic urethral lift (PUL), the temporary implantable nitinol device, and new intraprostatic implants. It analyzes the evidence for their safety, tolerability, and efficacy in clinical practice and aims to define those subpopulations of patients who will benefit from these MITs. It is obvious that there is a wide variation in the degree of mature of the available mechanical MITs. Time and high-quality long-term studies will decide which of these therapies will be accepted by patients and urologists. At the moment, PUL is claiming its position in the armamentarium of BPO treatment.

DOI10.1177/1756287219828971
Alternate JournalTher Adv Urol
PubMed ID30792821
PubMed Central IDPMC6376539

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