Decreased prolyl hydroxylase 3 mRNA expression in oncocytomas compared with clear cell renal cell carcinoma.
Τίτλος | Decreased prolyl hydroxylase 3 mRNA expression in oncocytomas compared with clear cell renal cell carcinoma. |
Publication Type | Journal Article |
Year of Publication | 2020 |
Authors | Kampantais, S., Kounatidis I., Kotoula V., Vakalopoulos I., Gkagkalidis K., & Dimitriadis G. |
Journal | Int J Biol Markers |
Pagination | 1724600820960478 |
Date Published | 2020 Oct 29 |
ISSN | 1724-6008 |
Abstract | INTRODUCTION: Hypoxia inducible factors (HIF) and prolyl hydroxylase domain (PHD) enzymes play a central role in tumor progression in clear cell renal cell carcinoma (ccRCC). However, there are currently no data regarding the behavior of this pathway (HIF/PHD) in a large number of benign renal tumors, the oncocytomas. The aim of the present study was to compare the expression levels of these factors between ccRCC and oncocytoma tumors. |
DOI | 10.1177/1724600820960478 |
Alternate Journal | Int J Biol Markers |
PubMed ID | 33118406 |