Detection of oncogenes in chronic pancreatitis.
Τίτλος | Detection of oncogenes in chronic pancreatitis. |
Publication Type | Journal Article |
Year of Publication | 2003 |
Authors | Paramythiotis, D., Kleeff J., Schmidt J., Büchler M. W., & Friess H. |
Journal | HPB (Oxford) |
Volume | 5 |
Issue | 4 |
Pagination | 214-25 |
Date Published | 2003 |
ISSN | 1365-182X |
Abstract | BACKGROUND: The pathogenesis of chronic pancreatitis (CP) remains poorly understood. Recently, molecular biology has identified the genetic background for many patients with hereditary CP. In addition, a number of studies have focused on the detection of proto-oncogenes and tumour suppressor gene mutations in the pathogenesis of CP. So far, the use of these mutations (with the exception of mutations causing hereditary CP), as diagnostic and prognostic markers is still controversial. |
DOI | 10.1080/13651820310017804 |
Alternate Journal | HPB (Oxford) |
PubMed ID | 18332990 |
PubMed Central ID | PMC2020596 |