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Dual-probe 24-hour ambulatory pH monitoring for diagnosis of laryngopharyngeal reflux.

ΤίτλοςDual-probe 24-hour ambulatory pH monitoring for diagnosis of laryngopharyngeal reflux.
Publication TypeJournal Article
Year of Publication2004
AuthorsIssing, W. J., Karkos P. D., Perreas K., Folwaczny C., & Reichel O.
JournalJ Laryngol Otol
Volume118
Issue11
Pagination845-8
Date Published2004 Nov
ISSN0022-2151
Λέξεις κλειδιάAdult, Aged, Anti-Ulcer Agents, Cough, Endoscopy, Gastrointestinal, Esomeprazole, Female, Gastroesophageal Reflux, Hoarseness, Humans, Hydrogen-Ion Concentration, Laryngeal Diseases, Male, Middle Aged, Monitoring, Ambulatory
Abstract

BACKGROUND: Patients with gastroesophageal reflux disease may suffer from a variety of symptoms from the upper aerodigestive tract. The objective of this study was to determine the impact of dual-probe 24-hr pH monitoring in the diagnosis of reflux-related otolaryngological disorders.
METHODS: Twenty-two patients with symptoms such as chronic cough, globus pharyngeus, heartburn, dysphonia and burning sensation of the tongue underwent a complete ear, nose and throat examination, 24-hr dual-probe pH monitoring, and oesophago-gastro-duodenoscopy.
RESULTS: pH monitoring revealed gastroesophageal (distal) reflux in all patients and pharyngeal (proximal) reflux in 21 patients. Treatment consisted of a proton pump inhibitor (esomeprazole). Within 4 weeks 68 per cent of patients had no laryngopharyngeal symptoms; within 8 weeks 95 per cent of patients were symptom-free.
CONCLUSIONS: Patients with atypical reflux symptoms such as hoarseness, globus sensation or throat-clearing responded well to anti-reflux treatment.

DOI10.1258/0022215042703660
Alternate JournalJ Laryngol Otol
PubMed ID15638969

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