Glycemic efficacy and safety of glucagon-like peptide-1 receptor agonist on top of sodium-glucose co-transporter-2 inhibitor treatment compared to sodium-glucose co-transporter-2 inhibitor alone: A systematic review and meta-analysis of RCTs.
Τίτλος | Glycemic efficacy and safety of glucagon-like peptide-1 receptor agonist on top of sodium-glucose co-transporter-2 inhibitor treatment compared to sodium-glucose co-transporter-2 inhibitor alone: A systematic review and meta-analysis of RCTs. |
Publication Type | Journal Article |
Year of Publication | 2019 |
Authors | Patoulias, D., Stavropoulos K., Imprialos K., Katsimardou A., Kalogirou M-S., Koutsampasopoulos K., Zografou I., Papadopoulos C., Karagiannis A., & Doumas M. |
Journal | Diabetes Res Clin Pract |
Volume | 158 |
Pagination | 107927 |
Date Published | 2019 Dec |
ISSN | 1872-8227 |
Abstract | OBJECTIVE: Sodium-glucose co-transporter-2 inhibitors (SGLT-2i) and glucagon-like peptide-1 receptor agonists (GLP-1RAs) are now considered as key players in the treatment of type 2 diabetes mellitus (T2DM). The purpose of this meta-analysis was to provide precise effect estimates regarding the safety and efficacy of the addition of a GLP-1RA on top of SGLT-2i treatment. |
DOI | 10.1016/j.diabres.2019.107927 |
Alternate Journal | Diabetes Res. Clin. Pract. |
PubMed ID | 31733280 |