Impact of the Model for End-stage Liver Disease (MELD) score on liver transplantation in Greece.
Τίτλος | Impact of the Model for End-stage Liver Disease (MELD) score on liver transplantation in Greece. |
Publication Type | Journal Article |
Year of Publication | 2014 |
Authors | Karapanagiotou, A., Kydona C., Dimitriadis C., Papadopoulos S., Theodoridou T., Tholioti T., Fouzas G., Imvrios G., & Gritsi-Gerogianni N. |
Journal | Transplant Proc |
Volume | 46 |
Issue | 9 |
Pagination | 3212-5 |
Date Published | 2014 Nov |
ISSN | 1873-2623 |
Λέξεις κλειδιά | End Stage Liver Disease, Female, Follow-Up Studies, Greece, Humans, Liver Transplantation, Male, Middle Aged, Preoperative Period, Retrospective Studies, Risk Assessment, Severity of Illness Index, Survival Rate, Time Factors |
Abstract | INTRODUCTION: The impact of preoperative Model for End-stage Liver Disease (MELD) score in postoperative mortality remains unclear. The assumption that patients with a higher MELD score will have a higher mortality rate is not confirmed and studies are contradictory.AIM: The study of the clinical course of patients with a higher MELD score and its impact in immediate and later mortality in comparison with patients with a lower MELD score in the only liver transplantation center in Greece.METHOD: We retrospectively studied 71 patients who underwent orthotopic liver transplantation (OLT) in the time period between 1-1-2011 and 31-12-2013. The patients were divided into 2 groups: Group A with a MELD score ≥23 and Group B with a MELD score <23.RESULTS: In the patients with a MELD score ≥23 the duration of mechanical ventilation and length of stay in the ICU were prolonged (P = .013 and .009, respectively), the transfusions were more (P = .005), and the rates of ICU readmissions (22.5% vs 7.31%, P = .001) and infections (42.5% vs 17.5%, P = .011) were higher. Thirty-day mortality did not differ between the 2 groups (P = .420), but there was a statistically significant difference in morbidity and in 180-day mortality.CONCLUSION: The patients with a higher MELD score have more complex pathophysiology. This score seems to affect morbidity and late, but not early, mortality. |
DOI | 10.1016/j.transproceed.2014.10.032 |
Alternate Journal | Transplant. Proc. |
PubMed ID | 25420862 |