Diabetes type 1 constitutes a growing problem for many children and adolescents worldwide. Diabetic children and adolescents are dependent on insulin for survival. Today, insulin treatment, either in the classic insulin forms or in the form of insulin analogs, is widely used in the pediatric diabetic population. New methods of insulin administration like the continuous subcutaneous insulin infusion systems (pumps) have been developed to ameliorate metabolic control and reduce diabetic complications.