Matrix metalloproteinases and peripheral arterial disease.
Τίτλος | Matrix metalloproteinases and peripheral arterial disease. |
Publication Type | Journal Article |
Year of Publication | 2015 |
Authors | Giagtzidis, I., Karkos C., Pitoulias G., & Papazoglou K. |
Journal | Int Angiol |
Volume | 34 |
Issue | 3 |
Pagination | 195-201 |
Date Published | 2015 Jun |
ISSN | 1827-1839 |
Λέξεις κλειδιά | Angioplasty, Balloon, Animals, Biomarkers, Comorbidity, Diabetes Mellitus, Disease Progression, Extracellular Matrix, Humans, Hypertension, Matrix Metalloproteinases, Peripheral Arterial Disease, Renal Insufficiency, Chronic |
Abstract | It has been postulated that atherosclerosis should be considered as a chronic inflammatory process and peripheral arterial disease (PAD) is a manifestation of such an atherosclerotic vascular disease. Matrix metalloproteinases (MMPs) are significant circulating biomarkers which play a pivotal role in the initiation, progression and clinical manifestations of PAD. This review summarizes the current body of evidence with regard to the association between MMPs and PAD. |
Alternate Journal | Int Angiol |
PubMed ID | 25069487 |