Δημοσίευση

Matrix metalloproteinases and peripheral arterial disease.

ΤίτλοςMatrix metalloproteinases and peripheral arterial disease.
Publication TypeJournal Article
Year of Publication2015
AuthorsGiagtzidis, I., Karkos C., Pitoulias G., & Papazoglou K.
JournalInt Angiol
Volume34
Issue3
Pagination195-201
Date Published2015 Jun
ISSN1827-1839
Λέξεις κλειδιάAngioplasty, Balloon, Animals, Biomarkers, Comorbidity, Diabetes Mellitus, Disease Progression, Extracellular Matrix, Humans, Hypertension, Matrix Metalloproteinases, Peripheral Arterial Disease, Renal Insufficiency, Chronic
Abstract

It has been postulated that atherosclerosis should be considered as a chronic inflammatory process and peripheral arterial disease (PAD) is a manifestation of such an atherosclerotic vascular disease. Matrix metalloproteinases (MMPs) are significant circulating biomarkers which play a pivotal role in the initiation, progression and clinical manifestations of PAD. This review summarizes the current body of evidence with regard to the association between MMPs and PAD.

Alternate JournalInt Angiol
PubMed ID25069487

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