Mycoplasma pneumoniae and Chlamydophila pneumoniae: a comparative study in patients with nasal polyposis and healthy controls.
Τίτλος | Mycoplasma pneumoniae and Chlamydophila pneumoniae: a comparative study in patients with nasal polyposis and healthy controls. |
Publication Type | Journal Article |
Year of Publication | 2015 |
Authors | Ioannidis, D. G., Lachanas V. A., Florou Z., Bizakis J. G., Petinaki E., & Skoulakis C. E. |
Journal | J Laryngol Otol |
Volume | 129 |
Issue | 9 |
Pagination | 865-9 |
Date Published | 2015 Sep |
ISSN | 1748-5460 |
Abstract | INTRODUCTION: The role played by Mycoplasma pneumoniae and Chlamydophila pneumoniae in the pathogenesis of chronic rhinosinusitis with nasal polyps has been the object of ongoing debate. We used real-time polymerase chain reaction to investigate the prevalence of both microorganisms in the nasal tissue samples of patients and controls.METHODS: We extracted DNA from nasal polyp samples obtained during functional endoscopic sinus surgery and the inferior turbinate samples of controls undergoing septoplasty. We used the highly sensitive real-time polymerase chain reaction to detect the presence of M pneumoniae and C pneumoniae DNA.RESULTS: Patients with chronic rhinosinusitis with nasal polyps consisted of 62 individuals (39 men; mean age 51 years); the control group consisted of 24 individuals (13 men; mean age 45 years). All samples from both groups were negative for M pneumoniae and C pneumoniae DNA.CONCLUSION: We have demonstrated that the likelihood of M pneumoniae and C pneumoniae acting as an ongoing inflammatory stimulus in chronic rhinosinusitis with nasal polyps is slim. |
DOI | 10.1017/S0022215115001590 |
Alternate Journal | J Laryngol Otol |
PubMed ID | 26223662 |