Opposite Prognostic Impact of Single PTEN-loss and Mutations in Early High-risk Breast Cancer.
Τίτλος | Opposite Prognostic Impact of Single PTEN-loss and Mutations in Early High-risk Breast Cancer. |
Publication Type | Journal Article |
Year of Publication | 2019 |
Authors | Lazaridis, G., Kotoula V., Vrettou E., Kostopoulos I., Manousou K., Papadopoulou K., Giannoulatou E., Bobos M., Sotiropoulou M., Pentheroudakis G., Efstratiou I., Papoudou-Bai A., Psyrri A., Christodoulou C., Gogas H., Koutras A., Timotheadou E., Pectasides D., Zagouri F., & Fountzilas G. |
Journal | Cancer Genomics Proteomics |
Volume | 16 |
Issue | 3 |
Pagination | 195-206 |
Date Published | 2019 May-Jun |
ISSN | 1790-6245 |
Abstract | BACKGROUND/AIM: PTEN-loss and PIK3CA mutations have been addressed as markers of PI3K activation in breast cancer. We evaluated these markers in early high-risk breast cancer (EBC) focusing on PTEN immunohistochemistry (IHC) issues, particularly in HER2-positive disease. |
DOI | 10.21873/cgp.20125 |
Alternate Journal | Cancer Genomics Proteomics |
PubMed ID | 31018950 |