Primary neuroendocrine neoplasms of the larynx. A series of 4 cases reported and a review of the literature.
| Τίτλος | Primary neuroendocrine neoplasms of the larynx. A series of 4 cases reported and a review of the literature. |
| Publication Type | Journal Article |
| Year of Publication | 2013 |
| Authors | Angouridakis, N., Goudakos J., Karayannopoulou G., Triaridis S., Nikolaou A., & Markou K. |
| Journal | Head Neck |
| Volume | 35 |
| Issue | 6 |
| Pagination | E187-93 |
| Date Published | 2013 Jun |
| ISSN | 1097-0347 |
| Λέξεις κλειδιά | Aged, Chemoradiotherapy, Chemotherapy, Adjuvant, Humans, Laryngeal Neoplasms, Laryngectomy, Male, Middle Aged, Neoplasm Metastasis, Neuroendocrine Tumors, Radiotherapy, Adjuvant, Retrospective Studies, Smoking, Thyroidectomy |
| Abstract | BACKGROUND: Neuroendocrine tumors are rare neoplasms arising from neural and epithelial origin.METHODS AND RESULTS: The case records of 4 patients with the diagnosis of neuroendocrine laryngeal tumor were retrospectively reviewed. In this analysis of our medical records, we describe a series of 4 men with neuroendocrine laryngeal tumors treated in our department since 1994, including the first extremely aggressive and lethal laryngeal paraganglioma reported in the English-language literature. We also discuss the classification, the macro and microscopical characteristics, clinical and pathologic findings, and treatment of these neoplasms.CONCLUSION: Although neuroendocrine laryngeal tumors account for approximately 1% of all neoplasms in the larynx, its majority represents very aggressive tumors showing a capacity for metastasis and portending poor outcome. |
| DOI | 10.1002/hed.22955 |
| Alternate Journal | Head Neck |
| PubMed ID | 22308009 |
