Progesterone rise on the day of human chorionic gonadotropin administration impairs pregnancy outcome in day 3 single-embryo transfer, while has no effect on day 5 single blastocyst transfer.
| Τίτλος | Progesterone rise on the day of human chorionic gonadotropin administration impairs pregnancy outcome in day 3 single-embryo transfer, while has no effect on day 5 single blastocyst transfer. |
| Publication Type | Journal Article |
| Year of Publication | 2009 |
| Authors | Papanikolaou, E. G., Kolibianakis E. M., Pozzobon C., Tank P., Tournaye H., Bourgain C., Van Steirteghem A., & Devroey P. |
| Journal | Fertil Steril |
| Volume | 91 |
| Issue | 3 |
| Pagination | 949-52 |
| Date Published | 2009 Mar |
| ISSN | 1556-5653 |
| Λέξεις κλειδιά | Adult, Chorionic Gonadotropin, Drug Therapy, Combination, Embryo Implantation, Embryo Transfer, Female, Fertility Agents, Female, Follicle Stimulating Hormone, Gonadotropin-Releasing Hormone, Hormone Antagonists, Humans, Luteal Phase, Ovulation Induction, Pregnancy, Pregnancy Outcome, Progesterone, Prospective Studies, Recombinant Proteins, Time Factors, Up-Regulation |
| Abstract | Four hundred eighty-two patients undergoing single ET with GnRH-antagonist/recFSH protocol were analyzed. The incidence of premature luteinization (P above 1.5 ng/mL on the day of hCG administration) was 18.2%. Even modest rises of P in the follicular phase have detrimental effect on the implantation potential of a good-quality cleavage stage embryo. On the contrary, premature luteinization in the blastocyst subgroup had no effect on the pregnancy outcome. |
| DOI | 10.1016/j.fertnstert.2006.12.064 |
| Alternate Journal | Fertil. Steril. |
| PubMed ID | 17555751 |
