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In quest of the missing neuron: spike sorting based on dominant-sets clustering.

ΤίτλοςIn quest of the missing neuron: spike sorting based on dominant-sets clustering.
Publication TypeJournal Article
Year of Publication2012
AuthorsAdamos, D. A., Laskaris N. A., Kosmidis E. K., & Theophilidis G.
JournalComput Methods Programs Biomed
Volume107
Issue1
Pagination28-35
Date Published2012 Jul
ISSN1872-7565
Λέξεις κλειδιάAction Potentials, Algorithms, Brain, Cluster Analysis, Electrodes, Electrophysiology, Humans, Models, Neurological, Neurons, Signal-To-Noise Ratio
Abstract

Spike sorting algorithms aim at decomposing complex extracellular signals to independent events from single neurons in the electrode's vicinity. The decision about the actual number of active neurons is still an open issue, with sparsely firing neurons and background activity the most influencing factors. We introduce a graph-theoretical algorithmic procedure that successfully resolves this issue. Dimensionality reduction coupled with a modern, efficient and progressively executable clustering routine proved to achieve higher performance standards than popular spike sorting methods. Our method is validated extensively using simulated data for different levels of SNR.

DOI10.1016/j.cmpb.2011.10.015
Alternate JournalComput Methods Programs Biomed
PubMed ID22136935

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