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Rivaroxaban Use in Patients with Hemoglobinopathies.

ΤίτλοςRivaroxaban Use in Patients with Hemoglobinopathies.
Publication TypeJournal Article
Year of Publication2017
AuthorsApostolou, C., Klonizakis P., Mainou M., Kapsali E., Kafantari K., Kotsiafti A., Vetsiou E., Vakalopoulou S., & Vlachaki E.
JournalHemoglobin
Volume41
Issue3
Pagination223-224
Date Published2017 May
ISSN1532-432X
Λέξεις κλειδιάAdult, Aged, Anemia, Sickle Cell, beta-Thalassemia, Factor Xa Inhibitors, Female, Follow-Up Studies, Hemoglobinopathies, Humans, Male, Middle Aged, Rivaroxaban, Stroke, Thromboembolism, Treatment Outcome
Abstract

The use of rivaroxaban in patients with hemoglobinopathies and thrombotic events has not been studied extensively. Here we present eight cases of such patients, five receiving rivaroxaban for stroke and systemic embolism prevention due to non-valvular atrial fibrillation and three for deep vein thrombosis treatment. The follow-up period ranged from 6 to 34 months. During this period none of the patients experienced any thrombotic or bleeding event.There were no other adverse events reported. Further studies with larger numbers of patients with hemoglobinopathies are needed to determine the use of rivaroxaban and ensure its safety in this patient setting.

DOI10.1080/03630269.2017.1374969
Alternate JournalHemoglobin
PubMed ID28950780

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