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Treatment of adynamic bone disease in a haemodialysis patient with teriparatide.

ΤίτλοςTreatment of adynamic bone disease in a haemodialysis patient with teriparatide.
Publication TypeJournal Article
Year of Publication2015
AuthorsGiamalis, P., Economidou D., Dimitriadis C., Memmos D., Papagianni A., & Efstratiadis G.
JournalClin Kidney J
Volume8
Issue2
Pagination188-90
Date Published2015 Apr
ISSN2048-8505
Abstract

Prevalence of adynamic bone disease (ABD), characterized by low bone turnover and absence or a reduced number of osteoblasts and osteoclasts, is increasing steadily over the last years. We present a dialysis patient, with recurrent bone fractures and biopsy-proven ABD, who was treated with teriparatide. Nine months after initiation of treatment, iPTH plasma levels increased to 520 pg/mL and a second bone biopsy revealed high bone turnover, normal mineralization and normal bone volume. Two years later, iPTH was 250-350 pg/dL and bone metabolism parameters within normal range. The probable utility of teriparatide in the treatment of ABD in dialysis patients is discussed.

DOI10.1093/ckj/sfv005
Alternate JournalClin Kidney J
PubMed ID25815175
PubMed Central IDPMC4370305

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