Update on current pancreatic treatments: from molecular pathways to treatment.
| Τίτλος | Update on current pancreatic treatments: from molecular pathways to treatment. |
| Publication Type | Journal Article |
| Year of Publication | 2019 |
| Authors | Sapalidis, K., Kosmidis C., Funtanidou V., Katsaounis A., Barmpas A., Koimtzis G., Mantalobas S., Alexandrou V., Aidoni Z., Koulouris C., Pavlidis E., Giannakidis D., Surlin V., Pantea S., Strambu V., Constantina R. Otilia, Amaniti A., Zarogoulidis P., Mogoanta S., Kesisoglou I., & Sardeli C. |
| Journal | J Cancer |
| Volume | 10 |
| Issue | 21 |
| Pagination | 5162-5172 |
| Date Published | 2019 |
| ISSN | 1837-9664 |
| Abstract | Pancreatic cancer is still diagnosed at a late stage although we have novel diagnostic tools. Pancreatic cancer chemotherapy treatment resistance is observed and therefore novel treatments are in need. Anti-cancer stem cell therapy, combination of chemotherapy and/or radiotherapy with immunotherapy, proteins/enzymes and gene therapy are currently under evaluation. Targeted treatment with tyrosine kinase inhibitors is also administered and novel inhibitors are also under evaluation. In the current review we present recent data from our search within the year 2018. |
| DOI | 10.7150/jca.36300 |
| Alternate Journal | J Cancer |
| PubMed ID | 31602269 |
| PubMed Central ID | PMC6775621 |
