Δημοσίευση

Update on the role of Interleukin 17 in rheumatologic autoimmune diseases.

ΤίτλοςUpdate on the role of Interleukin 17 in rheumatologic autoimmune diseases.
Publication TypeJournal Article
Year of Publication2015
AuthorsKonya, C., Paz, iv Z., Apostolidis S. A., & Tsokos G. C.
JournalCytokine
Volume75
Issue2
Pagination207-15
Date Published2015 Oct
ISSN1096-0023
Abstract

Interleukin 17 is a proinflammatory cytokine produced by CD4+ T cells when in the presence of a distinct set of cytokines and other cells. Preclinical and clinical studies have assigned a role to IL-17 in tissue inflammation and damage in patients with rheumatoid arthritis, psoriasis and psoriatic arthritis, ankylosing spondylitis and systemic lupus erythematosus. Antibodies blocking the action of IL-17 have already been approved to treat patients with psoriasis and it is expected that they may also benefit patients with other rheumatic diseases.

DOI10.1016/j.cyto.2015.01.003
Alternate JournalCytokine
PubMed ID26028353

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