Urinary tract infections caused by extended-spectrum betalactamase-producing bacteria in children: a matched casecontrol study.
Τίτλος | Urinary tract infections caused by extended-spectrum betalactamase-producing bacteria in children: a matched casecontrol study. |
Publication Type | Journal Article |
Year of Publication | 2013 |
Authors | Dotis, J., Printza N., Marneri A., Gidaris D., & Papachristou F. |
Journal | Turk J Pediatr |
Volume | 55 |
Issue | 6 |
Pagination | 571-4 |
Date Published | 2013 Nov-Dec |
ISSN | 0041-4301 |
Λέξεις κλειδιά | Anti-Bacterial Agents, beta-Lactamases, Case-Control Studies, Child, Child, Preschool, Female, Follow-Up Studies, Gram-Negative Bacteria, Gram-Negative Bacterial Infections, Humans, Incidence, Infant, Male, Retrospective Studies, Risk Factors, Turkey, Urinary Tract Infections |
Abstract | Extended-spectrum beta-lactamase (ESBL)-producing pathogens are emerging as a cause of urinary tract infections (UTI) worldwide. In this matched-case control study, clinical characteristics and associated risk factors for ESBL UTI were evaluated. In a total of 463 positive urine cultures, 48 (10.4%) (from 39 patients, 23 boys) were phenotypically ESBL-producing bacteria. The most frequently isolated microorganism was , followed by Klebsiella spp. and Enterobacter cloacae. Children with ESBL UTI (n=39) were on prophylaxis more (21% vs. 6%, p=0.01), had higher rates of urinary tract anomalies (36% vs. 10%, p=0.0007), presented abnormal 99m Tcdimercaptosuccinic acid (DMSA) findings (i.e. scars) (23% vs. 4%, p=0.001), and had longer hospitalization (9.8 vs. 7.4 days, p=0.004) compared to those with non-ESBL UTI (n=117). The recognition of risk factors for UTI caused by ESBL bacteria in children may aid in the identification of high-risk cases and may enable proper management of these patients. |
Alternate Journal | Turk. J. Pediatr. |
PubMed ID | 24577973 |