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Lipid Layers on Polyelectrolyte Multilayers: Understanding Lipid-Polyelectrolyte Interactions and Applications on the Surface Engineering of Nanomaterials.

TitleLipid Layers on Polyelectrolyte Multilayers: Understanding Lipid-Polyelectrolyte Interactions and Applications on the Surface Engineering of Nanomaterials.
Publication TypeJournal Article
Year of Publication2016
AuthorsDiamanti, E., Gregurec D., Gabriela R., Cuellar J. L., Donath E., & Moya S. E.
JournalJ Nanosci Nanotechnol
Volume16
Issue6
Pagination5696-700
Date Published2016 Jun
ISSN1533-4880
KeywordsBiological Transport, Engineering, Hep G2 Cells, Humans, Intracellular Space, Lactic Acid, Lipid Bilayers, Models, Molecular, Molecular Conformation, Nanoparticles, Nanotechnology, Nanotubes, Carbon, Polyglycolic Acid, Quartz Crystal Microbalance Techniques, Surface Properties
Abstract

In this manuscript we review work of our group on the assembly of lipid layers on top of polyelectrolyte multilayers (PEMs). The assembly of lipid layers with zwitterionic and charged lipids on PEMs is studied as a function of lipid and polyelectrolyte composition by the Quartz Crystal Microbalance. Polyelectrolyte lipid interactions are studied by means of Atomic Force Spectroscopy. We also show the coating of lipid layers for engineering different nanomaterials, i.e., carbon nanotubes and poly(lactic-co-glycolic) nanoparticles and how these can be used to decrease in vitro toxicity and to direct the intracellular localization of nanomaterials.

Alternate JournalJ Nanosci Nanotechnol
PubMed ID27427617

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