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Vitamin D and cardiovascular disease: From atherosclerosis to myocardial infarction and stroke.

TitleVitamin D and cardiovascular disease: From atherosclerosis to myocardial infarction and stroke.
Publication TypeJournal Article
Year of Publication2017
AuthorsMuscogiuri, G., Annweiler C., Duval G., Karras S., Tirabassi G., Salvio G., Balercia G., Kimball S., Kotsa K., Mascitelli L., Bhattoa H. Pal, & Colao A.
JournalInt J Cardiol
Volume230
Pagination577-584
Date Published2017 Mar 01
ISSN1874-1754
KeywordsAtherosclerosis, Humans, Myocardial Infarction, Stroke, Vitamin D, Vitamin D Deficiency, Vitamins
Abstract

There continues to be interest in understanding the role of vitamin D in the pathogenesis, epidemiology and prevention of cardiovascular disease (CVD). In fact vitamin D deficiency has been associated to an increased risk of developing CVD given to the relationship between low vitamin D levels and obesity, diabetes mellitus, dyslipidaemia, endothelial dysfunction and hypertension. However, although vitamin D has been identified as a potentially important marker of CVD, the mechanisms through which vitamin D deficiency leads from endothelial dysfunction to myocardial infarction and stroke are not fully understood. Thus, the goal of this review is to provide an updated review of the literature on the basic science of how vitamin D may affect the cardiovascular system and in particular to analyze the role that vitamin D may have in the whole dynamic process from the initiation of endothelial dysfunction to the development of myocardial infarction and stroke.

DOI10.1016/j.ijcard.2016.12.053
Alternate JournalInt. J. Cardiol.
PubMed ID28043680

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