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Antegrade vs Crossover Femoral Artery Access in the Endovascular Treatment of Isolated Below-the-Knee Lesions in Patients With Critical Limb Ischemia.

TitleAntegrade vs Crossover Femoral Artery Access in the Endovascular Treatment of Isolated Below-the-Knee Lesions in Patients With Critical Limb Ischemia.
Publication TypeJournal Article
Year of Publication2017
AuthorsLi, Y., Esmail A., Donas K. P., Pitoulias G., Torsello G., Bisdas T., Michelagnoli S., & Troisi N.
JournalJ Endovasc Ther
Volume24
Issue3
Pagination331-336
Date Published2017 06
ISSN1545-1550
KeywordsAged, Aged, 80 and over, Angioplasty, Balloon, Critical Illness, Disease-Free Survival, Female, Femoral Artery, Germany, Humans, Ischemia, Italy, Lower Extremity, Male, Middle Aged, Peripheral Arterial Disease, Punctures, Retrospective Studies, Risk Factors, Stents, Time Factors, Treatment Outcome, Vascular Patency
Abstract

PURPOSE: To evaluate the safety and effectiveness of antegrade vs crossover femoral artery access in the endovascular treatment of isolated below-the-knee (BTK) lesions in patients with critical limb ischemia (CLI).METHODS: Between January 2014 and December 2015, 224 high-risk patients (mean age 75.8±9.8 years; 151 men) with CLI underwent infragenicular interventions on 292 crural vessels in 3 European vascular centers. All patients had isolated TransAtlantic Inter-Society Consensus (TASC) C (n=26) or D (n=198) BTK lesions. Primary endpoints were freedom from access-related complications and technical success comparing the antegrade vs crossover access groups.RESULTS: Balloon angioplasty was the most used treatment modality (169 vessels, 75.4%). The technical success rate was 88.4% in the entire cohort and 88.0% in the antegrade group vs 90.4% in the crossover group (p>0.99). In all patients, the technical success rate was higher for stenotic lesions (100%) vs occlusions (85.5%, p=0.002) and in patients with TASC C BTK lesions (100%) vs TASC D (86.9%, p=0.033). The overall freedom from access-related complications was 97.8%: 99% in the antegrade group and 90.6% in the crossover group (p=0.022). Larger sheath size (5/6-F vs 4-F) was associated with a significantly higher risk for access-related complications (7.1% vs 1.1%, respectively; p=0.047).CONCLUSION: The present multicenter study showed high technical success and a low incidence of access-related complications in the treatment of isolated BTK lesions using either antegrade or crossover femoral access. The antegrade approach with the use of a 4-F system seems to have a significantly lower rate of access-related complications.

DOI10.1177/1526602817701251
Alternate JournalJ. Endovasc. Ther.
PubMed ID28378609

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