Scar tissue to lung cancer; pathways and treatment.
Title | Scar tissue to lung cancer; pathways and treatment. |
Publication Type | Journal Article |
Year of Publication | 2019 |
Authors | Sapalidis, K., Sardeli C., Pavlidis E., Koimtzis G., Koulouris C., Michalopoulos N., Mantalovas S., Tsiouda T., Passos I., Kosmidis C., Giannakidis D., Surlin V., Katsaounis A., Alexandrou V., Amaniti A., Zarogoulidis P., Huang H., Li Q., Mogoanta S., & Kesisoglou I. |
Journal | J Cancer |
Volume | 10 |
Issue | 4 |
Pagination | 810-818 |
Date Published | 2019 |
ISSN | 1837-9664 |
Abstract | Lung cancer still remains diagnosed at a late stage although we have novel diagnostic techniques at our disposal. However; for metastatic disease we have novel therapies based on pharmacogenomics. Tumor heterogenity provides us different treatments. There are several reasons for carcinogenesis; fibrosis and scar tissue provides an environment that induces malignancy. In the current review we will try and elucidate the pathways involved from scar tissue to carcinogenesis. |
DOI | 10.7150/jca.30300 |
Alternate Journal | J Cancer |
PubMed ID | 30854086 |
PubMed Central ID | PMC6400809 |