The MELAS syndrome. Review of the literature: the role of the otologist.
Title | The MELAS syndrome. Review of the literature: the role of the otologist. |
Publication Type | Journal Article |
Year of Publication | 2004 |
Authors | Karkos, P. D., Waldron M., & Johnson I. J. |
Journal | Clin Otolaryngol Allied Sci |
Volume | 29 |
Issue | 1 |
Pagination | 1-4 |
Date Published | 2004 Feb |
ISSN | 0307-7772 |
Keywords | DNA, Mitochondrial, Hearing Loss, Sensorineural, Humans, MELAS Syndrome, Otolaryngology, Physician's Role |
Abstract | The mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) syndrome is a rare congenital disorder of mitochondrial DNA (mt-DNA). Patients with this syndrome may present to the otolaryngologist with sensorineural hearing loss (SNHL), which is genetic in origin. A high index of suspicion is required because this hearing loss is part of a syndrome for which early diagnosis and intervention is required. |
DOI | 10.1111/j.1365-2273.2004.00769.x |
Alternate Journal | Clin Otolaryngol Allied Sci |
PubMed ID | 14961844 |