The english version of the website is under development. Wherever text appears in Greek, it means it has not been translated yet.

Δημοσίευση

Is there a role for the otolaryngologist in PFAPA syndrome? A systematic review.

TitleIs there a role for the otolaryngologist in PFAPA syndrome? A systematic review.
Publication TypeJournal Article
Year of Publication2006
AuthorsLeong, S. C. L., Karkos P. D., & Apostolidou M. T.
JournalInt J Pediatr Otorhinolaryngol
Volume70
Issue11
Pagination1841-5
Date Published2006 Nov
ISSN0165-5876
KeywordsChild, Fever, Humans, Lymphadenitis, Neck, Otolaryngology, Pharyngitis, Stomatitis, Aphthous, Syndrome, Tonsillectomy
Abstract

AIMS: To define the role of medical or surgical treatment in patients with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA syndrome).
METHODS: A Medline search was performed using the terms PFAPA, periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis, treatment. A systematic review of the English literature was performed. Papers on pyrexia of unknown origin in the pediatric population were excluded; this was because the clinical entities included in the differential diagnosis of pyrexia of unknown origin share many clinical characteristics with PFAPA, and may be ill defined.
RESULTS: Twenty-seven papers have been published since 1989, of which 20 were in English language. There were five single case reports and two papers involving two patients each. There were 6 retrospective reviews of case notes, involving 5-94 patients over a 3-10 year review period. Given that current evidence on the effectiveness of tonsillectomy in PFAPA is extremely weak (level of evidence V), tonsillectomy should not be performed.
CONCLUSIONS: PFAPA usually resolves without any long-term adverse effect, and as such, there is no role for tonsillectomy in these patients.

DOI10.1016/j.ijporl.2006.07.002
Alternate JournalInt. J. Pediatr. Otorhinolaryngol.
PubMed ID16908073

Contact

Secretariat of the School of Medicine
 

Connect

School of Medicine's presence in social networks
Follow Us or Connect with us.