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Efficacy of microneedling with topical vitamin C in the treatment of melasma.

TitleEfficacy of microneedling with topical vitamin C in the treatment of melasma.
Publication TypeJournal Article
Year of Publication2019
AuthorsIsmail, E. Salah Ali, Patsatsi A., El-Maged W. Mohammed A., & Nada E. El- Din Abd
JournalJ Cosmet Dermatol
Date Published2019 Feb 15
ISSN1473-2165
Abstract

BACKGROUND: Despite the wide therapeutic options available for the treatment of melasma, including many active topical medications, technologies with lights and peelings, clinical control of this disorder is extremely challenging.
OBJECTIVES: To evaluate the effect of microneedling with topical vitamin C in the treatment of melasma.
METHODS: Thirty female patients with melasma received six sessions of microneedling with addition of topical vitamin C every two weeks. At each session, photos were taken and Melasma Area and Severity Index (MASI) score was calculated to assess the clinical improvement.
RESULTS: Mean age of the eligible patients was 33.2 ± 5.77 years. About 50% of cases were of Fitzpatrick skin type III. All patients showed improvement at the end of the sessions. Mean MASI score in the first session was 8.61 ± 4.45 and there was a gradual decline in its value till it reached a mean of 5.75 ± 4.16 in the last session (P < 0.0001).
CONCLUSION: Microneedling with topical vitamin C is an effective and safe treatment option for epidermal melasma especially in Fitzpatrick skin phototypes I-III.

DOI10.1111/jocd.12878
Alternate JournalJ Cosmet Dermatol
PubMed ID30770637
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