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Producing the appropriate model and drug for intratumoural ablation.

TitleProducing the appropriate model and drug for intratumoural ablation.
Publication TypeJournal Article
Year of Publication2020
AuthorsKosmidis, C., Sardeli C., Zarogoulidis P., Hohenforst-Schmidt W., Vagionas A., Ioannis-Katsios N., & Sapalidis K.
JournalBr J Cancer
Volume123
Issue3
Pagination335-336
Date Published2020 Aug
ISSN1532-1827
Abstract

Local treatment is necessary for several cancer patients. There are situations where cancer tissue induces locally severe symptoms. Therefore, additional local disease control is necessary. There are two major issues for efficient local treatment: the method of application and the penetration of the drug formulation. We need efficient tools to guide the drug formulation to the target point, and an effective drug formulation that is diffused within the tumour microenvironment with a sustained-release effect.

DOI10.1038/s41416-020-0895-6
Alternate JournalBr J Cancer
PubMed ID32457363
PubMed Central IDPMC7403372

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