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Acute pneumothorax due to immunotherapy administration in non-small cell lung cancer.

TitleAcute pneumothorax due to immunotherapy administration in non-small cell lung cancer.
Publication TypeJournal Article
Year of Publication2020
AuthorsSardeli, C., Zarogoulidis P., Romanidis K., Oikonomou P., Sapalidis K., Huang H., Bai C., Hohenforst-Schmidt W., Tsakiridis K., Zaric B., Perin B., Ioannidis A., Baka S., Drevelegas K., Kosmidou M., & Kosmidis C.
JournalRespir Med Case Rep
Volume31
Pagination101258
Date Published2020
ISSN2213-0071
Abstract

Nowadays we have novel therapies for advanced stage non-small cell lung cancer. Immunotherapy has been introduced in the market for several years and until now its administration is mostly based on the programmed death-ligand 1. First line treatment with immunotherapy can be administered alone if programmed death-ligand 1 expression is ≥ 50%. All therapies for advanced stage disease have advantages and disadvantages, immunotherapy until now has presented mild adverse effects when compared to chemotherapy. However; it is known to induce inflammatory response to different tissues within the body. In our case acute pneumothorax was induced after immunotherapy administration.

DOI10.1016/j.rmcr.2020.101258
Alternate JournalRespir Med Case Rep
PubMed ID33145157
PubMed Central IDPMC7596337

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