An association study of sodium-lithium countertransport activity with glutathione S transferase (GST) T1 and GST M1 null polymorphisms in Greek dyslipidaemic patients and controls.
Title | An association study of sodium-lithium countertransport activity with glutathione S transferase (GST) T1 and GST M1 null polymorphisms in Greek dyslipidaemic patients and controls. |
Publication Type | Journal Article |
Year of Publication | 2008 |
Authors | Goulas, A., Kosmidou M., Hatzitolios A. I., Raikos N., Molyva D., Savopoulos C., Giannopoulos S., & Fidani L. |
Journal | Clin Chem Lab Med |
Volume | 46 |
Issue | 3 |
Pagination | 306-10 |
Date Published | 2008 |
ISSN | 1434-6621 |
Keywords | Antiporters, Case-Control Studies, Dyslipidemias, Erythrocytes, Female, Glutathione Transferase, Greece, Humans, Hypertension, Ion Transport, Lithium, Male, Middle Aged, Polymorphism, Genetic, Protein Binding, Sodium |
Abstract | BACKGROUND: Previous genomic linkage studies have produced evidence linking sodium-lithium countertransport activity (Na/Li CT) with various chromosomal regions including loci harbouring glutathione S transferase (GST) genes. The aim of this study was to examine the putative association of erythrocyte Na/Li CT activity with GST T1 and M1 gene null polymorphisms. |
DOI | 10.1515/CCLM.2008.065 |
Alternate Journal | Clin Chem Lab Med |
PubMed ID | 18254710 |