l-selenomethionine supplementation in children and adolescents with autoimmune thyroiditis: A randomized double-blind placebo-controlled clinical trial.
Title | l-selenomethionine supplementation in children and adolescents with autoimmune thyroiditis: A randomized double-blind placebo-controlled clinical trial. |
Publication Type | Journal Article |
Year of Publication | 2019 |
Authors | Kyrgios, I., Giza S., Kotanidou E. P., Kleisarchaki A., Tsinopoulou V. Rengina, Papadopoulou A., Markantonatou A-M., Kanellidou E., Giannakou A., & Galli-Tsinopoulou A. |
Journal | J Clin Pharm Ther |
Volume | 44 |
Issue | 1 |
Pagination | 102-108 |
Date Published | 2019 Feb |
ISSN | 1365-2710 |
Keywords | Adolescent, Child, Child, Preschool, Dietary Supplements, Double-Blind Method, Female, Humans, Male, Selenomethionine, Thyroid Gland, Thyroiditis, Autoimmune, Treatment Outcome |
Abstract | WHAT IS KNOWN AND OBJECTIVE: Although a beneficial effect of selenium (Se) administration has been proposed in adults with autoimmune thyroiditis (AT), there is a paucity of similar data in children and adolescents. The purpose of the study was to investigate whether administration of a high dose of organic Se (200 μg daily as l-selenomethionine) has an effect on antithyroid antibody titres in children and adolescents with AT. |
DOI | 10.1111/jcpt.12765 |
Alternate Journal | J Clin Pharm Ther |
PubMed ID | 30306604 |