4,4'-Methylenedianiline-induced hepatitis in an industrial worker: case report and review of the literature.
| Title | 4,4'-Methylenedianiline-induced hepatitis in an industrial worker: case report and review of the literature. |
| Publication Type | Journal Article |
| Year of Publication | 2011 |
| Authors | Giouleme, O., Karabatsou S., Hytiroglou P., Xanthis A., Tsiaousi E., Katsaros M., & Koliouskas D. |
| Journal | Hum Exp Toxicol |
| Volume | 30 |
| Issue | 7 |
| Pagination | 762-7 |
| Date Published | 2011 Jul |
| ISSN | 1477-0903 |
| Keywords | Acute Disease, Adult, Allergens, Aniline Compounds, Drug-Induced Liver Injury, Humans, Liver, Liver Function Tests, Male, Methylprednisolone, Occupational Diseases, Treatment Outcome |
| Abstract | 4,4'-Methylenedianiline (MDA) is a chemical used in manufacturing and insulation processes and is a well-known hepatotoxin. We report the case of a 42-year-old construction-site worker who was accidentally exposed to large amounts of MDA and developed acute liver damage. The clinical course is described, with particular emphasis on the timely identification of the underlying cause and prompt management that led to an uneventful recovery. We review the relevant literature and discuss the safety measures necessary to minimize similar occupational hazards in industrial workers. |
| DOI | 10.1177/0960327110376549 |
| Alternate Journal | Hum Exp Toxicol |
| PubMed ID | 20621954 |
