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The role of cytokines in pulp inflammation.

TitleThe role of cytokines in pulp inflammation.
Publication TypeJournal Article
Year of Publication2011
AuthorsKokkas, A., Goulas A., Stavrianos C., & Anogianakis G.
JournalJ Biol Regul Homeost Agents
Volume25
Issue3
Pagination303-11
Date Published2011 Jul-Sep
ISSN0393-974X
KeywordsAnimals, Cytokines, Dental Pulp, Gene Expression Regulation, Humans, Inflammation, Pulpitis
Abstract

Pulpitis is a typical inflammatory disease of dental pulp, characterized by the local accumulation of inflammatory mediators, including cytokines and chemokines. In addition to serving as intercellular messengers mediating the inflammatory response, cytokines and chemokines induce the expression and stimulate the activity of molecular and cellular agents which participate actively in destructive and reparative processes in the pulp. It is the balance between these processes which eventually determines the extent of pulp inflammation and the viability of the affected tooth. Over the last decade, a number of studies have attempted to correlate cytokine gene expression in the pulp with various stages of inflammation, with possible diagnostic applications in mind. A small survey of relevant information is presented in this paper.

Alternate JournalJ. Biol. Regul. Homeost. Agents
PubMed ID22023754

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