Evaluation of Oral Glucose Tolerance Test in Children With Epilepsy.
Title | Evaluation of Oral Glucose Tolerance Test in Children With Epilepsy. |
Publication Type | Journal Article |
Year of Publication | 2013 |
Authors | Varlamis, S., Vavatsi N., Pavlou E., Kotsis V., Spilioti M., Kavga M., Varlamis G., Sotiriadou F., Agakidou E., Voutoufianakis S., & Evangeliou A. E. |
Journal | J Child Neurol |
Volume | 28 |
Issue | 11 |
Pagination | 1437-1442 |
Date Published | 2013 Nov |
ISSN | 1708-8283 |
Abstract | Glucose metabolism of children with drug-resistant epilepsy, controlled by antiepileptic drugs epilepsy, and first-time nonfebrile seizures was studied through the performance of an oral glucose tolerance test and through insulin, C-peptide, and glycosylated hemoglobin measurements. In the refractory epilepsy group, there were more abnormal oral glucose tolerance test results (62.07%) in comparison to the controlled epilepsy group (25%) and the group of first-time seizures (21.21%). There was a significant difference between the group of refractory epilepsy and every other group concerning the abnormality of the oral glucose tolerance test (P < .05). The mean values of insulin, HbA1c, and C-peptide levels were normal for all groups. The results of the present study suggest that there is a distinction of refractory epilepsies from the drug-controlled ones and the first-induced seizures relating to their metabolic profile, regardless of the type of seizures. |
DOI | 10.1177/0883073812460919 |
Alternate Journal | J. Child Neurol. |
PubMed ID | 23071070 |