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Bilateral secondary neurolymphomatosis of the internal auditory canal nerves: a case report.

TitleBilateral secondary neurolymphomatosis of the internal auditory canal nerves: a case report.
Publication TypeJournal Article
Year of Publication2013
AuthorsBlioskas, S., Tsaligopoulos M., Kyriafinis G., Psillas G., Markou K., Perifanis V., Kouskouras K., & Vital V.
JournalAm J Otolaryngol
Volume34
Issue5
Pagination556-8
Date Published2013 Sep-Oct
ISSN1532-818X
KeywordsAnimals, Cochlear Nerve, Combined Modality Therapy, Diagnosis, Differential, Ear, Inner, Hearing Loss, Sensorineural, Humans, Magnetic Resonance Imaging, Male, Marek Disease, Middle Aged
Abstract

BACKGROUND: Neurolymphomatosis describes the malignant lymphomatous infiltration of nerves.METHODS: We encountered a unique case of a 47-year-old patient with non-Hodgkin's lymphoma presenting with bilateral sensorineural hearing loss, vestibular dysfunction and bilateral facial nerve palsy.RESULTS: Magnetic resonance imaging demonstrated enhancement and thickening of internal auditory canal nerves bilaterally consistent with neurolymphomatosis. Patient was treated with combined intrathecal chemotherapy and total brain irradiation.CONCLUSIONS: One must always remain vigilant for metastatic disease in patients with sensorineural hearing loss and/or vestibular dysfunction and facial nerve palsy in the context of known malignancy.

DOI10.1016/j.amjoto.2013.04.002
Alternate JournalAm J Otolaryngol
PubMed ID23993712

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