Ancient human genomes suggest three ancestral populations for present-day Europeans.
Title | Ancient human genomes suggest three ancestral populations for present-day Europeans. |
Publication Type | Journal Article |
Year of Publication | 2014 |
Authors | Lazaridis, I., Patterson N., Mittnik A., Renaud G., Mallick S., Kirsanow K., et al. |
Journal | Nature |
Volume | 513 |
Issue | 7518 |
Pagination | 409-13 |
Date Published | 2014 Sep 18 |
ISSN | 1476-4687 |
Keywords | Agriculture, Asia, Europe, European Continental Ancestry Group, Genome, Human, History, Ancient, Humans, Population Dynamics, Principal Component Analysis |
Abstract | We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old hunter-gatherers from Luxembourg and Sweden. We analysed these and other ancient genomes with 2,345 contemporary humans to show that most present-day Europeans derive from at least three highly differentiated populations: west European hunter-gatherers, who contributed ancestry to all Europeans but not to Near Easterners; ancient north Eurasians related to Upper Palaeolithic Siberians, who contributed to both Europeans and Near Easterners; and early European farmers, who were mainly of Near Eastern origin but also harboured west European hunter-gatherer related ancestry. We model these populations' deep relationships and show that early European farmers had ∼44% ancestry from a 'basal Eurasian' population that split before the diversification of other non-African lineages. |
DOI | 10.1038/nature13673 |
Alternate Journal | Nature |
PubMed ID | 25230663 |
PubMed Central ID | PMC4170574 |
Grant List | 8DP1ES022577-04 / DP / NCCDPHP CDC HHS / United States GM100233 / GM / NIGMS NIH HHS / United States GM40282 / GM / NIGMS NIH HHS / United States HG002385 / HG / NHGRI NIH HHS / United States HG004120 / HG / NHGRI NIH HHS / United States HHSN26120080001E / / PHS HHS / United States P01 HG004120 / HG / NHGRI NIH HHS / United States R01 GM100233 / GM / NIGMS NIH HHS / United States R01 HG002385 / HG / NHGRI NIH HHS / United States R01 HG006399 / HG / NHGRI NIH HHS / United States / / Howard Hughes Medical Institute / United States / / Intramural NIH HHS / United States |