Double- and multi-carbapenemase-producers: the excessively armored bacilli of the current decade.
Title | Double- and multi-carbapenemase-producers: the excessively armored bacilli of the current decade. |
Publication Type | Journal Article |
Year of Publication | 2015 |
Authors | Meletis, G., Chatzidimitriou D., & Malisiovas N. |
Journal | Eur J Clin Microbiol Infect Dis |
Volume | 34 |
Issue | 8 |
Pagination | 1487-93 |
Date Published | 2015 Aug |
ISSN | 1435-4373 |
Keywords | Bacterial Proteins, beta-Lactamases, Cross Infection, Drug Resistance, Multiple, Bacterial, Global Health, Gram-Negative Bacteria, Gram-Negative Bacterial Infections, Humans |
Abstract | Multidrug-resistant (MDR) and extensively drug-resistant (XDR) Gram-negative nosocomial pathogens commonly carry one carbapenemase gene conferring resistance to carbapenems and other beta-lactam antibiotics. However, increasing reports show that double-carbapenemase-producing (DCP) and even multi-carbapenemase-producing (MCP) bacteria are emerging in some parts of the world, diminishing further, in some cases, the already limited treatment options. In the present review, the up-to-date reports of DCP and MCP isolates are summarized and concerns regarding their emergence are discussed. |
DOI | 10.1007/s10096-015-2379-9 |
Alternate Journal | Eur. J. Clin. Microbiol. Infect. Dis. |
PubMed ID | 25894987 |