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Coexistence of squamous cell tracheal papilloma and carcinoma treated with chemotherapy and radiotherapy: a case report.

TitleCoexistence of squamous cell tracheal papilloma and carcinoma treated with chemotherapy and radiotherapy: a case report.
Publication TypeJournal Article
Year of Publication2016
AuthorsPaliouras, D., Gogakos A., Rallis T., Chatzinikolaou F., Asteriou C., Tagarakis G., Organtzis J., Tsakiridis K., Tsavlis D., Zissimopoulos A., Kioumis I., Hohenforst-Schmidt W., Zarogoulidis K., Zarogoulidis P., & Barbetakis N.
JournalTher Clin Risk Manag
Volume12
Pagination1-4
Date Published2016
ISSN1176-6336
Abstract

BACKGROUND: Papillomatosis presents, most frequently, as multiple lesions of the respiratory tract, which are usually considered benign. Malignant degeneration into squamous cell carcinoma is quite common, although curative approaches vary a lot in modern literature.CASE REPORT: We report a case of a 66-year-old male patient with the coexistence of multiple squamous cell papilloma and carcinoma in the upper trachea with severe airway obstruction that was diagnosed through bronchoscopy and treated by performing an urgent tracheostomy, followed by concurrent chemotherapy and radiotherapy. There was no evidence of recurrence after a 12-month follow-up period.CONCLUSION: This study underlines the diagnostic and therapeutic value of bronchoscopy as well as multimodality palliative treatment in such cases. To the best of our knowledge, this is the first study to describe an immediate treatment protocol with tracheostomy and concurrent chemotherapy/radiotherapy in a patient with squamous cell tracheal papilloma and carcinoma.

DOI10.2147/TCRM.S95233
Alternate JournalTher Clin Risk Manag
PubMed ID26730195
PubMed Central IDPMC4694660

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