Effect of early bosentan administration on the development of esophageal varices in cirrhotic rats: experimental study in Wistar rats.
Title | Effect of early bosentan administration on the development of esophageal varices in cirrhotic rats: experimental study in Wistar rats. |
Publication Type | Journal Article |
Year of Publication | 2008 |
Authors | Rafailidis, S., Ballas K., Psarras K., Pavlidis T., Emoniotou E., Papamichali R., Kalodimos G., Marakis G., Sakadamis A., & Koukoulis G. |
Journal | J Gastroenterol |
Volume | 43 |
Issue | 11 |
Pagination | 897-904 |
Date Published | 2008 |
ISSN | 0944-1174 |
Keywords | Animals, Antihypertensive Agents, Bosentan, Disease Progression, Dose-Response Relationship, Drug, Drug Administration Schedule, Esophageal and Gastric Varices, Follow-Up Studies, Liver, Liver Cirrhosis, Experimental, Male, Portal Pressure, Rats, Rats, Wistar, Sulfonamides, Time Factors, Treatment Outcome |
Abstract | BACKGROUND: This study was conducted to investigate the effect of chronic bosentan administration on the development of esophageal varices in carbon tetrachloride-induced cirrhosis in rats. |
DOI | 10.1007/s00535-008-2243-0 |
Alternate Journal | J Gastroenterol |
PubMed ID | 19012044 |