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A prospective international Aspergillus terreus survey: an EFISG, ISHAM and ECMM joint study.

TitleA prospective international Aspergillus terreus survey: an EFISG, ISHAM and ECMM joint study.
Publication TypeJournal Article
Year of Publication2017
AuthorsRisslegger, B., Zoran T., Lackner M., Aigner M., Sánchez-Reus F., Rezusta A., Chowdhary A., Taj-Aldeen S. J., Arendrup M. C., Oliveri S., Kontoyiannis D. P., Alastruey-Izquierdo A., Lagrou K., G Cascio L., Meis J. F., Buzina W., Farina C., Drogari-Apiranthitou M., Grancini A., Tortorano A. M., Willinger B., Hamprecht A., Johnson E., Klingspor L., Arsic-Arsenijevic V., Cornely O. A., Meletiadis J., Prammer W., Tullio V., Vehreschild J-J., Trovato L., Lewis R. E., Segal E., Rath P-M., Hamal P., Rodriguez-Iglesias M., Roilides E., Arikan-Akdagli S., Chakrabarti A., Colombo A. L., Fernández M. S., Martin-Gomez M. T., Badali H., Petrikkos G., Klimko N., Heimann S. M., Houbraken J., Uzun Ö., Edlinger M., de la Fuente S., & Lass-Florl C.
JournalClin Microbiol Infect
Volume23
Issue10
Pagination776.e1-776.e5
Date Published2017 Oct
ISSN1469-0691
KeywordsAmphotericin B, Antifungal Agents, Aspergillosis, Aspergillus, Epidemiological Monitoring, Europe, Humans, Microbial Sensitivity Tests, Prevalence, Prospective Studies
Abstract

OBJECTIVES: A prospective international multicentre surveillance study was conducted to investigate the prevalence and amphotericin B susceptibility of Aspergillus terreus species complex infections.METHODS: A total of 370 cases from 21 countries were evaluated.RESULTS: The overall prevalence of A. terreus species complex among the investigated patients with mould-positive cultures was 5.2% (370/7116). Amphotericin B MICs ranged from 0.125 to 32 mg/L, (median 8 mg/L).CONCLUSIONS: Aspergillus terreus species complex infections cause a wide spectrum of aspergillosis and the majority of cryptic species display high amphotericin B MICs.

DOI10.1016/j.cmi.2017.04.012
Alternate JournalClin. Microbiol. Infect.
PubMed ID28412383

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