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A breast fibroadenoma mimicking an extranodal deposit of Hodgkin's lymphoma in 67Ga imaging.

TitleA breast fibroadenoma mimicking an extranodal deposit of Hodgkin's lymphoma in 67Ga imaging.
Publication TypeJournal Article
Year of Publication2009
AuthorsMoralidis, E., Mandala E., Venizelos I., Arsos G., Zafiriadu E., Goutzioulis M., & Karakatsanis C.
JournalBr J Radiol
Volume82
Issue975
Paginatione58-62
Date Published2009 Mar
ISSN1748-880X
KeywordsBreast Neoplasms, Contrast Media, Diagnosis, Differential, False Positive Reactions, Female, Fibroadenoma, Gallium Radioisotopes, Hodgkin Disease, Humans, Lymphatic Metastasis, Tomography, X-Ray Computed, Treatment Outcome, Young Adult
Abstract

We present the case of a young woman with classical nodular sclerosing Hodgkin's lymphoma (clinical stage IIB). During staging work-up, intense gallium-67 ((67)Ga) accumulation in a left breast lump raised the suspicion of an extranodal deposit, but biopsy favoured a benign histology. A post-treatment (67)Ga scan showed complete remission of the disease with normal tracer uptake in the left breast. However, a few months after treatment, a faint left mammary concentration of (67)Ga was observed. The breast mass was excised and histopathology was consistent with fibroadenoma. This unusual presentation is a new addition to the literature on false-positive (67)Ga findings and chemotherapy-associated tracer changes.

DOI10.1259/bjr/40678458
Alternate JournalBr J Radiol
PubMed ID19211906

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