Polyarteritis nodosa in a patient with type 1 autoimmune hepatitis.
Title | Polyarteritis nodosa in a patient with type 1 autoimmune hepatitis. |
Publication Type | Journal Article |
Year of Publication | 2011 |
Authors | Giouleme, O., Mpoumponaris A., Aslanidis S., Anagnostis P., Giamalis P., Nikolaidis N., Vasiliadis T., & Evgenidis N. |
Journal | South Med J |
Volume | 104 |
Issue | 1 |
Pagination | 49-52 |
Date Published | 2011 Jan |
ISSN | 1541-8243 |
Keywords | Antibodies, Antinuclear, Biopsy, Diagnosis, Differential, Female, Follow-Up Studies, Hepatitis, Autoimmune, Humans, Kidney, Liver, Magnetic Resonance Angiography, Middle Aged, Polyarteritis Nodosa |
Abstract | Polyarteritis nodosa is a systemic necrotizing vasculitis that affects small- and medium-sized arteries. Liver involvement in patients with polyarteritis nodosa has been described, and ranges from asymptomatic elevation of aminotransferases to hepatic aneurysm rupture. We describe the case of a patient with type 1 autoimmune hepatitis and compensated liver cirrhosis who developed classic polyarteritis nodosa, complicated with cytomegalovirus and repeated urinary tract infections. After a long bedridden hospitalization, the patient's condition was stabilized. She is currently in good health, with well-controlled blood pressure, and stable kidney and liver function. To our knowledge, this is the first case report in the literature with concurrent appearance of both diseases. |
DOI | 10.1097/SMJ.0b013e3181fd0be6 |
Alternate Journal | South. Med. J. |
PubMed ID | 21119556 |