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Polyarteritis nodosa in a patient with type 1 autoimmune hepatitis.

TitlePolyarteritis nodosa in a patient with type 1 autoimmune hepatitis.
Publication TypeJournal Article
Year of Publication2011
AuthorsGiouleme, O., Mpoumponaris A., Aslanidis S., Anagnostis P., Giamalis P., Nikolaidis N., Vasiliadis T., & Evgenidis N.
JournalSouth Med J
Volume104
Issue1
Pagination49-52
Date Published2011 Jan
ISSN1541-8243
KeywordsAntibodies, Antinuclear, Biopsy, Diagnosis, Differential, Female, Follow-Up Studies, Hepatitis, Autoimmune, Humans, Kidney, Liver, Magnetic Resonance Angiography, Middle Aged, Polyarteritis Nodosa
Abstract

Polyarteritis nodosa is a systemic necrotizing vasculitis that affects small- and medium-sized arteries. Liver involvement in patients with polyarteritis nodosa has been described, and ranges from asymptomatic elevation of aminotransferases to hepatic aneurysm rupture. We describe the case of a patient with type 1 autoimmune hepatitis and compensated liver cirrhosis who developed classic polyarteritis nodosa, complicated with cytomegalovirus and repeated urinary tract infections. After a long bedridden hospitalization, the patient's condition was stabilized. She is currently in good health, with well-controlled blood pressure, and stable kidney and liver function. To our knowledge, this is the first case report in the literature with concurrent appearance of both diseases.

DOI10.1097/SMJ.0b013e3181fd0be6
Alternate JournalSouth. Med. J.
PubMed ID21119556

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