Comparing Abbott m2000 RealTime HIV test and Roche COBAS Ampliprep/COBAS Taqman HIV test, v2.0 in treated HIV-1 B and non-B subjects with low viraemia.
| Title | Comparing Abbott m2000 RealTime HIV test and Roche COBAS Ampliprep/COBAS Taqman HIV test, v2.0 in treated HIV-1 B and non-B subjects with low viraemia. |
| Publication Type | Journal Article |
| Year of Publication | 2016 |
| Authors | Margariti, A., Chatzidimitriou D., Metallidis S., Pilalas D., Kourelis A., Papadimitriou E., Haidich A-B., Malisiovas N., & Skoura L. |
| Journal | J Med Virol |
| Volume | 88 |
| Issue | 4 |
| Pagination | 724-7 |
| Date Published | 2016 Apr |
| ISSN | 1096-9071 |
| Abstract | Viral load testing is a valuable tool in HIV clinical care and research. Discrepancies among diverse viral load assays, especially with regard to non-B HIV-1 subtypes have been reported. Our study aimed to explore the impact of HIV subtype (B versus non-B) on the agreement between CAP/CTM, v2.0 and m2000 RealTime in treated HIV patients, focusing on low viral loads (<200 copies/ml). Our findings indicate that there is a significant difference in the performance of the compared assays in the low-viremic range and non-B subtypes, suggesting that a single assay should be used for follow-up. J. Med. Virol. 88:724-727, 2016. © 2015 Wiley Periodicals, Inc. |
| DOI | 10.1002/jmv.24369 |
| Alternate Journal | J. Med. Virol. |
| PubMed ID | 26331699 |
