Concurrent presentation of nodal myeloid sarcoma and bone marrow chronic lymphocytic leukemia/small lymphocytic lymphoma: a unique association.
Τίτλος | Concurrent presentation of nodal myeloid sarcoma and bone marrow chronic lymphocytic leukemia/small lymphocytic lymphoma: a unique association. |
Publication Type | Journal Article |
Year of Publication | 2014 |
Authors | Perifanis, V., Diamantidis M. D., Chalvatzi K., Kaloutsi V., Markala D., Voulgaridou V., Pantelidou P., Pavlidis A., Stavrou G., & Kaiafa G. |
Journal | Int J Hematol |
Volume | 99 |
Issue | 4 |
Pagination | 508-12 |
Date Published | 2014 Apr |
ISSN | 1865-3774 |
Λέξεις κλειδιά | Aged, Antigens, Surface, Biopsy, Bone Marrow, Female, Humans, Immunophenotyping, Leukemia, Lymphocytic, Chronic, B-Cell, Lymph Nodes, Sarcoma, Myeloid |
Abstract | Myeloid sarcoma (MS), previously known as granulocytic sarcoma, is a rare, localized, tumor mass composed of myeloid precursor cells, with or without maturation, and occurring at an anatomical site other than the bone marrow (BM). Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), in contrast, is a B-cell hematological malignancy. We describe the first reported case of concurrent presentation of nodal MS and of BM CLL/SLL in the same patient. Fatal leukemic central nervous system infiltration was the final outcome. We provide possible explanations and investigate the pathophysiology of this unique, previously unreported co-morbidity. |
DOI | 10.1007/s12185-014-1508-z |
Alternate Journal | Int. J. Hematol. |
PubMed ID | 24504438 |